Автор: Mark C. Rogge and David R. Taft Название: Preclinical Drug Development Издательство: CRC Press Год: 2005 ISBN: 978-1574448825 Серия: Drugs and the Pharmaceutical Sciences (Book 152) Язык: English Формат: pdf Размер: 26,8 mb Страниц: 600
Topics range from assessment of pharmacology and toxicology through the regulatory expectations that support clinical trials. Providing chapters on pharmacokinetics, modeling and simulation, formulation and routes of administration, toxicity evaluations, the assessment of drug absorption and metabolism, and interspecies scaling, this guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.