Автор: Werner Kalow; Urs A Meyer; Rachel Tyndale
Название: Pharmacogenomics
Издательство: New York: Marcel Dekker
Год: 2001
ISBN: 978-0824705442
Серия: Drugs and the pharmaceutical sciences (Book 113)
Язык: English
Формат: pdf
Размер: 28,8 mb
Страниц: 403
The term pharmacogenomics is a recent arrival in the literature, but it is a term that anyone interested in pharmacogenetics cannot overlook. The increasing prevalence of the term reflects the progressive transition from genetics to genomics that is taking place in pharmaceutical science. The most famous research in genomics is a worldwide program called the Human Genome Project, a massive effort that is expected to change the science of human biology, including our understanding of human disease. For anyone concerned with drugs and pharmacology, the arrival of the term pharmacogenomics is a reflection of this broad change.
Historical aspects of pharmacogenetics / Werner Kalow
Pharmacogenomics biomarkers, and the promise of personalized medicine / B. Michael Silber
Current status : pharmacogenetics/drug metabolism / Leif Bertilsson
Pharmacogentics receptors / Wendell W. Weber
Pharmacogentics of drug transporters / Richard B. Kim, Grant R. Wilkenson
Interethnic differences in drug response / Werner Kalow
Pharmacogentics : clinical viewpoints / Urs. A. Meyer
Tools of the trade : the technologies and challenges of pharmocogenetics / Glenn A. Miller
Molecular diagnostics and development of biotechnology-based diagnostics / Tracy L. Stockley, Peter N. Ray
Technologies for the analysis of single-nucleotide polymorphism : an overview / Denis M. Cerant, Michael S. Phillips
Multiplex fluorescent minisequencing applied to the typing of genes encoding drug-metabolizing enzymes / Gisela Sitbon, Ann-Christine Syva?nen
Multiplex genotyping by specialized mass spectrometry / Phillip L. Ross [and others]
Serial analysis of gene expression : transcriptional insights and functional biology / Stephen L. Madden, Clarence Wang, Greg Landes
Proteomics / Frank A. Witzmann
Bioinformatics : WWW resources / Siu Tang, Daiga Helmeste
Applied bioinformatics / David L. Hydman, Masato Mitsuhashi
Mapping of disease loci / Glenys Thomson
Positional cloning and disease gene identification / Mark S. Silverberg, Andrew P. Boright, Katherine A. Siminovitch
General conclusions and future directions / Werner Kalow, Arno G. Motulsky.
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