Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling PerspectiveКНИГИ » ЗДОРОВЬЕ И МЕДИЦИНА
Автор: Hui Kimko and Stephen B. Duffull Название: Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective Издательство: CRC Press Год: 2002 ISBN: 978-0824708627 Серия: Drugs and the Pharmaceutical Sciences (Book 127) Язык: English Формат: pdf Размер: 14,1 mb Страниц: 424
The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.